\item Go to the \texttt{bin} folder in the OTB install directory and double-click on the \texttt{.bat} file corresponding to the application to be run, for instance:\\
\item Execute in the python console : import numpy
\item Execute in the python console : import otbApplication
\end{enumerate}
If no error message is printed after the import commands, everything is fine. If not, check the Python version (2.7 or 3.5), and the PATH,OTB_APPLICATION_PATH and PYTHONPATH variables.